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Nik operon
The ''nik'' operon is an operon required for uptake of nickel ions. It is present in many bacteria, but has been extensively studied in ''Helicobacter pylori''. Nickel is an essential nutrient for many microorganisms, where it participates in a variety of cellular processes. Excessive levels of nickel ions in cell can be fatal to the cell. Nickel ion concentration in the cell is regulated through the ''nik'' operon. == Structure of the ''nik'' operon ==
The ''nik'' operon consists of six genes. The first five genes ''nikABCDE'' encode components of a typical ABC transport system and the last gene ''nikR'' encodes a DNA-binding protein that represses transcription of ''nikABCDE'' when sufficient Ni2+ is present. The ''nikR'' gene is located 5 bp downstream of the end of ''nikE'', transcribed in the same direction as ''nikABCDE''. The following table summarizes the structure of the ''nik'' operon:
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Nik operon」の詳細全文を読む
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